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  Stephen W.Attwood

【简介】

Stephen W.Attwood, 男,教授/博士生导师。

目前正在合作研究人类相关疾病的进化学,比如,癌症以及病毒感染。在过去几年已经应用进化学理论对寄生虫流行病学以及对疾病的起源和扩散进行了深入研究。现在正在将进化学方法也应用至生物治疗药物领域。

长期在四川大学生物治疗国家重点实验室从事研究,另外与很多其他学校,比如牛津大学,英国金斯顿大学以及广东和香港的大学的科研人员都有合作。过去曾经获得的主要科研基金1个来自中国的自然科学基金,2个来自UKRC3个来自Wellcome Trust grants

【职位】

·                     教授,生物治疗国家重点实验室,四川大学

·                     客座教授,自然历史博物馆,伦敦

·                     访问研究员,金斯顿大学,英国

【教育背景】

博士学位,Queen Mary University of London,英国

学士学位,Aberystwyth,英国

【主要研究方向】

1.   进化模型在癌症生物治疗药物中的应用

2.   采用改进的方法追踪病毒流行病

3.   利用种群遗传学去研究疾病模式

【招生信息】

目前研究要接触到的方面主要有组织培养,流式细胞仪,DNA/基因组测序以及生物信息学。欢迎遗传学学生或者具有该领域强项或者非常感兴趣的优秀学生来报考(博士、硕士)。

【邮箱】 cdt2008ss@hotmail.co.uk

【最近文章】

Huo, G.-N., Liu, L., He, H.-B. and Attwood, S. W. (2016). An investigation into the potential effects of infrapopulation structure and other sources of sampling error, on population genetic studies of the transmission of Schistosoma japonicum (Trematoda: Digenea). Parasites & Vectors, 9: 165.

Attwood, S. W., Ibaraki, M., Saitoh, Y., Nihei, N. and Janies, D. A. (2015). Comparative Phylogenetic Studies on Schistosoma japonicum and Its Snail Intermediate Host Oncomelania hupensis: Origins, Dispersal and Coevolution. PLoS Negl Trop Dis, 9: e0003935.

Attwood, S. W., Huo, G.-N. and Qiu, J.-W. (2014). Update on the distribution and phylogenetics of Biomphalaria (Gastropoda: Planorbidae) populations in Guangdong Province China. Acta Tropica 141B: 258-270. 

Liu, L., Huo, G.-N., He, H.-B., Zhou, B. and Attwood, S. W. (2014). A phylogeny for the pomatiopsidae (Gastropoda: Rissooidea): a resource for taxonomic, parasitological and biodiversity studies. BMC Evolutionary Biology, 14: 29.

Attwood, S. W. and Upatham, E. S. (2013). A Population Growth Trend Analysis for Neotricula aperta, the Snail Intermediate Host of Schistosoma mekongi, after Construction of the Pak-Mun Dam. PLOS Neglected Tropical Diseases, 7: e2539.

 

 

Self-introduction:

I am currently interested in harnessing evolutionary theory in the management of human diseases such as cancer and viral infections. In the past I have applied evolutionary theory to parasite epidemiology and the study of the origins and spread of diseases. I am now transferring these evolutionary approaches to biotherapeutics.

In addition to a long period of service in the SKLB, I am a visiting professor at the Natural History Museum, London and I have collaborations with the University of Oxford, Kingston University in London, and Universities in Guangdong and Hong Kong. I have obtained past funding through three Wellcome Trust grants, two UKRC, and one China NSF grant, as well as numerous smaller awards and prizes.

Appointments

·                     Professor, State Key Laboratory of Biotherapy

·                     Visiting Professor Natural History Museum, London

·                     Visiting Researcher, Kingston University, UK

Administrative Appointments

·                     Associate Editor PLOS Neglected Tropical Diseases

·                     Advisor Mekong Biodiversity Programme

Academic Qualifications

·                     PhD, Queen Mary University of London, United Kingdom

·                     BSc (Hons), Aberystwyth, United Kingdom

Main Research Directions

·                     Evolutionary models in cancer therapeutics

·                     Improved approaches to tracking viral epidemics

·                     Landscape genetics in understanding patterns of disease

Recruitment Information

Current work focuses on tissue culture, flow cytometry, DNA-sequencing/genomics and bioinformatics. We may have opportunities for outstanding PhD or master students with strengths in these areas or specific majors to the recruitment section 'with strengths in these areas (e.g. majors in genetics ...)

Selected Recent Publications

Huo, G.-N., Liu, L., He, H.-B. and Attwood, S. W. (2016). An investigation into the potential effects of infrapopulation structure and other sources of sampling error, on population genetic studies of the transmission of Schistosoma japonicum (Trematoda: Digenea). Parasites & Vectors, 9: 165.

Attwood, S. W., Ibaraki, M., Saitoh, Y., Nihei, N. and Janies, D. A. (2015). Comparative Phylogenetic Studies on Schistosoma japonicum and Its Snail Intermediate Host Oncomelania hupensis: Origins, Dispersal and Coevolution. PLoS Negl Trop Dis, 9: e0003935.

Attwood, S. W., Huo, G.-N. and Qiu, J.-W. (2014). Update on the distribution and phylogenetics of Biomphalaria (Gastropoda: Planorbidae) populations in Guangdong Province China. Acta Tropica 141B: 258-270. 

Liu, L., Huo, G.-N., He, H.-B., Zhou, B. and Attwood, S. W. (2014). A phylogeny for the pomatiopsidae (Gastropoda: Rissooidea): a resource for taxonomic, parasitological and biodiversity studies. BMC Evolutionary Biology, 14: 29.

Attwood, S. W. and Upatham, E. S. (2013). A Population Growth Trend Analysis for Neotricula aperta, the Snail Intermediate Host of Schistosoma mekongi, after Construction of the Pak-Mun Dam. PLOS Neglected Tropical Diseases, 7: e2539.

 

生物治疗国家重点实验室 管理入口
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